UWTV Program: Balancing the Fat Equation

Search:

Search for information by:

Note: Selected programs are available for streaming download per agreement with the original media source.

Sponsored by:

Balancing the Fat Equation

	A family of proteins called PPARs (peroxisome proliferator-activator receptors) controls how the body uses sugar and fat. PPAR-gamma drives the formation of fat cells and regulates the storage of fat. It encourages muscles to burn sugar and maintains insulin sensitivity. PPAR-delta regulates how muscles burn fat by stimulating cellular fat-burning pathways and increasing slow-twitch muscle mass, which primarily uses fat as an energy source. Mice that are engineered to produce an overactive version of this receptor in their muscle tissue remain sleek and lean. On a treadmill, these 'marathon mice' run twice as far as normal mice. Drugs that stimulate PPARs might help people slim down and improve health without altering appetite.



	* Help?
	* Help?
	Captions are available for this video. Learn how to view captions.


	Audio (MP3) \| Video (MPEG-4) Note: If you have trouble saving a file because it opens within a media player, right-click on the link and select "Save Target/Link As..."


	Subscribe to the series Podcast (Podcast Help) Audio (MP3) \| Video (MPEG-4)
Speaker(s):	Ronald M. Evans, Ph.D., HHMI Investigator, The Salk Institute for Biological Studies
Related Link(s):	Biointeractive web site
Production Date:	12/03/2004
Runtime:	00:58:30
Rating:	TV-G